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News
31 August, 2024
Ground-breaking find in bladder cancer study
Researchers at the Frazer Institute, University of Queensland, have uncovered a critical mechanism by which bladder cancer evades the immune system.
This finding, detailed in eBioMedicine, reveals that bladder cancer suppresses natural killer (NK) cells by releasing a protein known as TGF-ẞ.
Targeting this protein could lead to innovative therapies, potentially within three to five years.
Associate Professor Fernando Guimaraes, who led the research, emphasised the significance of unlocking the power of immunotherapy.
His team’s discovery was made by PhD candidate Joshua Wong, who described it as a “eureka moment.”
The research is poised to advance to clinical trials, exploring TGF-ẞ inhibitors in combination with NK cell-based therapies.
Bladder cancer, the ninth most common malignancy globally, affected over 3,000 Australians last year.
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